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HIV Prevention That Works:

Learn about PEP and PrEP

Two poweful tools for everyone to protect their health. 
Available now at HOPE.

 Learn more about two powerful medications available now at HOPE that can stop HIV, even after exposure. Find out how you can get emergency PEP or daily PrEP even if you don’t have insurance. Cost should never be a barrier. HOPE connects patients with savings programs and assistance.

Your health, your choice, your HOPE.

What is PEP

  • Emergency medication you take after a possible HIV exposure
  • Must be started within 72 hours
  • Taken for 28 days
  • Helps prevent HIV from taking hold in your body

What is PrEP?

  • A daily pill or injection that protects you before exposure
  • Up to 99% effective when taken correctly
  • Helps you stay HIV negative with peace of mind

Who should consider it?

PEP and PrEP are for everyone – regardless of gender or sexual orientation

PEP may be right for you if you:

  • Had unprotected vaginal or anal sex in the past 72 hours with someone HIV-positive or unknown status
  • Were exposed to blood through a needle stick, open wound, or mucous membrane

PrEP may be right for you if you:

  • Have a partner with HIV
  • Have had unprotected vaginal or anal sex in the last six months
  • Have had a recent STI
  • Share needles or injection tools

About PEP

PEP is a powerful emergency option if you’ve been recently exposed to HIV. Exposure can occur through unprotected vaginal or anal sex, sharing of injection drug tools, or transfer of blood and bodily fluids from an HIV positive individual.

To be effective, PEP must:

  • Be stated within 72 hours of exposure. It is not recommended for exposure over 72 hours ago or for negligible risks (saliva, sweat, urine)
  • Taken for 28 days
  • Follow-up HIV and STI testing is recommended at 4-6 weeks, three months and six months

Financial help is available for prescriptions.

Learn more from the CDC.

Call the HOPE Hotline

If you think you might be a candidate for PEP, call the HOPE hotline at (918) 416-0577.

Call the HOPE Hotline

If you think you might be a candidate for PrEP, call the HOPE hotline at (918) 416-0577.

About PrEP

PrEP gives you the freedom to take control of your health. It’s for anyone who want long-term protection against HIV.
  • Daily pill or injection
  • Up to 99% effective at preventing HIV when taken as prescribed
  • Recommended for adults and teens (13+) who are HIV negative
  • Requires HIV and STI testing every 3–6 months
  • Options include Truvada®, Descovy®, and Apretude®

Learn more from the CDC.

Leading the HOPE care team

Dr. Valerie Howard

Dr. Valerie Howard, D.O., FACOI, is HOPE’s Medical Director. She is board-certified in Internal Medicine, a Fellow of the American College of Osteopathic Internists, and earned her Doctor of Osteopathy from Oklahoma State University. She is affiliated with Saint Francis Hospital and Ascension St. John Medical Center.
At HOPE, Dr. Howard leads our PEP and PrEP programs, ensuring care is accessible, confidential, and supportive for everyone. Her approach is rooted in compassion and evidence-based medicine.
“I’m dedicated to helping each person protect their health in the way that works best for them — whether that’s PEP, PrEP, or support along the way.”

Dr. Matthew Else earned his Doctor of Osteopathy from Oklahoma State University. His mission is to equip his patients with the knowledge and tools they need to make informed lifestyle choices that promote long-term wellness through a welcoming and judgment-free environment. 

Juliette Kross, Advanced Practice Registered Nurse, Nurse Practitioner is board certified as a Family Nurse Practitioner and practices at her rural clinic JA Family Medicine, LLC in Wagoner, OK. She prides herself on building genuine connections because she believes that where medicine begins.

FAQs

Do I need a prescription for PEP or PrEP?

Yes, both PEP and PrEP require a prescription. Call HOPE at (918) 416-0577 to request an appointment for PEP and/or PrEP.

What is the difference between PEP and PrEP?
PEP is for emergencies only. It is taken AFTER exposure has occured and works to keep the infected cells from replicating. It is critical that PEP be started within 72 hours of exposure. PrEP is a daily medication taken by HIV negative individuals to safeguard them against contracting HIV if they are ever exposed through unprotected sex, needle pricks or other bodily fluid exposure with someone who has HIV. It’s important to note that PrEP does not prevent other STIs or pregnancy.
Is PEP and PrEP safe?

Yes, both PEP and PrEP are safe, effective and CDC recommended.

Do I need insurance?

HOPE believes insurance should not be a barrier to receiving services. We can assist patients with or without insurance coverage. Do not let insurance or cost hinder treatment.

How much does PEP or PrEP cost?

PEP and PrEP are covered by most private health insurances, Medicare and Medicaid. If you do not have health insurance, HOPE can help you find financial assistance to help cover the costs of these prescriptions. Do not let insurance or cost hinder treatment.

What if I don't have a way to get to the clinic?

f you do not have reliable transportation, and live in eastern Oklahoma (generally east of I-35), please let us know and we will arrange for transportation to get you to and from the HOPE Testing clinic at 4720 E. 51st St.

Next steps

Getting Started at HOPE

1.

Call the HOPE hotline at (918) 416-0577 or request an appointment online.

2.

Meet with Dr. Howard or HOPE’s prevention team.

3.

Same-day labs and prescriptions are often available. Our team will work with you to provide timely treatment and support.

4.

Receive ongoing follow-up and care to stay healthy.

 

Cost should never be a barrier. HOPE connects patients with savings programs and assistance.

Why choose HOPE?

Same-day or next-day appointments

Confidential and judgement free care

Help with insurance and prescription costs